The Diabetes project in PAZAR Help

Description

Gene regulation in diabetes

Statistics

Regulated genes (or markers): 54
Regulatory sequences (genomic): 92
Regulatory sequences (artificial): 1
Transcription factors: 15
Transcription factor profiles: 0
Annotated publications: 31

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Homo sapiens
Mus musculus
Rattus norvegicus
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chromosome
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actin-related protein T2 ENSMUSG00000051276
ADP-ribosylation factor-like 4D ENSMUSG00000034936
ATPase, H+ transporting, lysosomal accessory protein 2 ENSMUSG00000031007
autophagy-related 9A ENSMUSG00000033124
carnitine O-octanoyltransferase ENSMUSG00000003623
chromodomain helicase DNA binding protein 7 ENSMUSG00000041235
collagen, type XXV, alpha 1 ENSMUSG00000058897
crystallin, alpha A ENSMUSG00000024041
ecotropic viral integration site 5 like ENSMUSG00000011832
erythrocyte protein band 41-like 3 ENSMUSG00000024044
family with sequence similarity 131, member C ENSMUSG00000006218
family with sequence similarity 134, member B ENSMUSG00000022270
family with sequence similarity 3, member B ENSMUSG00000022938
Gastric inhibitory polypeptide ENSRNOG00000006306
glucokinase ENSMUSG00000041798
glucose-6-phosphatase, catalytic, 2 ENSMUSG00000005232
immunity-related GTPase family M member 1 ENSMUSG00000046879
insulin II ENSMUSG00000000215
Insulin-1Insulin-1 B chainInsulin-1 A chain ENSRNOG00000012052
Insulin-2Insulin-2 B chainInsulin-2 A chain ENSRNOG00000020405
insulinoma-associated 1 ENSMUSG00000068154
Iroquois related homeobox 1 ENSMUSG00000060969
isocitrate dehydrogenase 1 , soluble ENSMUSG00000025950
M-phase phosphoprotein 10 ENSMUSG00000030521
mastermind like 3 ENSMUSG00000061143
MYST histone acetyltransferase 2 ENSMUSG00000038909
NADH dehydrogenase 1 beta subcomplex, 9 ENSMUSG00000022354
neurogenic differentiation 1 ENSMUSG00000034701
neuronatin ENSMUSG00000067786
NK2 transcription factor related, locus 2 ENSMUSG00000027434
nuclear receptor subfamily 5, group A, member 2 ENSG00000116833
nuclear receptor subfamily 5, group A, member 2 ENSMUSG00000026398
olfactory receptor 1408 ENSMUSG00000062527
paired box gene 6 ENSMUSG00000027168
pancreatic and duodenal homeobox 1 ENSMUSG00000029644
pancreatic and duodenal homeobox 1 ENSG00000139515
phospholipase C, beta 1 ENSMUSG00000051177
pleckstrin homology domain containing, family A member 6 ENSMUSG00000041757
protein phosphatase 2 , gamma isoform ENSMUSG00000029120
RAB GTPase activating protein 1-like ENSMUSG00000026721
regulatory factor X, 3 ENSMUSG00000040929
ribosomal protein L26, pseudogene 1 ENSMUSG00000075184
RIKEN cDNA 3110082I17 gene ENSMUSG00000053553
RIKEN cDNA G930045G22 gene ENSMUSG00000073072
single-stranded DNA binding protein 3 ENSMUSG00000061887
solute carrier family 22, member 23 ENSMUSG00000038267
SomatostatinAntrinSomatostatin-28Somatostatin-14 ENSRNOG00000001837
TIP41, TOR signalling pathway regulator-like ENSMUSG00000040843
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 ENSMUSG00000038462
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A ENSMUSG00000047591
X Kell blood group precursor related family member 4 ENSMUSG00000051951
xylosyltransferase 1 ENSMUSG00000030657
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HELIX-TURN-HELIX GROUP
HELIX-TURN-HELIX GROUP
OTHER
WINGED HELIX-TURN-HELIX
ZINC-COORDINATING GROUP
ZIPPER-TYPE GROUP
Restrict to protein-DNA interaction quality »
Restrict to sequences where interaction is
Restrict to expression outcome »
Restrict to sequences where expression is
Restrict to one or more evidence types »
ADMC
curated
predicted
Restrict to one or more experimental methods »
15688014
COMPILED
COMPUTATIONAL PREDICTION
DNASE I FOOTPRINTING
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::DIRECT GEL SHIFT
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::DIRECT GEL SHIFT WITH WESTERN BLOT DETECTION
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::GEL SHIFT COMPETITION
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::SUPERSHIFT
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::UNKNOWN
EMSA
EXPERT CURATED::LITERATURE DERIVED
GENE CO-EXPRESSION::CO-EXPRESSED GENES DETERMINED THROUGH REPORTER GENE EXPERIMENTS
IN-VIVO HUMAN CD4 ASSAY
MUTAGENESIS::EXONUCLEASE DIGESTION
MUTAGENESIS::EXONUCLEASE III DIGESTION
MUTAGENESIS::OLIGONUCLEOTIDE SYNTHESIS
MUTAGENESIS::PCR
MUTAGENESIS::RESTRICTION ENDONUCLEASE DIGESTION
MUTAGENESIS::SITE-DIRECTED
MUTAGENESIS::UNKNOWN
N/A
NA
PROTEIN BINDING ASSAY :: CHROMATIN IMMUNOPRECIPITATION WITH TAG SEQUENCING (CHIP-TS)
PROTEIN BINDING ASSAY::CHROMATIN IMMUNOPRECIPITATION (CHIP)
PROTEIN BINDING ASSAY::CHROMATIN IMMUNOPRECIPITATION WITH TAG SEQUENCING (CHIP-TS)
PROTEIN BINDING ASSAY::DNA-PROTEIN PRECIPITATION ASSAY
PROTEIN BINDING ASSAY::DNA-PROTEIN PRECIPITATION ASSAY WITH ELISA DETECTION
PROTEIN BINDING ASSAY::DNASE FOOTPRINTING ASSAY
PROTEIN BINDING ASSAY::DNASE FOOTPRINTING COMPETITION ASSAY
PROTEIN BINDING ASSAY::IN-VIVO FOOTPRINTING ASSAY
PROTEIN BINDING ASSAY::METHYLATION INTERFERENCE
PROTEIN BINDING ASSAY::METHYLATION INTERFERENCE ASSAY
PROTEIN BINDING ASSAY::UNKNOWN
PROTEIN BINDING ASSAY::WESTERN BLOT ASSAY
PROTEIN BINDING ASSAY::YEAST 1-HYBRID ASSAY
PROTEIN EXPRESSION ASSAY::ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA)
PROTEIN EXPRESSION ASSAY::INDIRECT IMMUNOFLUORESCENCE
PROTEIN EXPRESSION ASSAY::LUCIFERASE EXPRESSION ASSAY
PROTEIN EXPRESSION ASSAY::WESTERN BLOT ASSAY
REPORTER GENE ASSAY
REPORTER GENE ASSAY:: TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY
REPORTER GENE ASSAY:: TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY WITH ELISA DETECTION
REPORTER GENE ASSAY::BETA-GLOBIN EXPRESSION ASSAY
REPORTER GENE ASSAY::CHLORAMPHENICOL ACETYLTRANSFERASE (CAT) ASSAY
REPORTER GENE ASSAY::DUAL LUCIFERASE REPORTER GENE ASSAY
REPORTER GENE ASSAY::IN-VITRO VIRUS REPLICATION ASSAY
REPORTER GENE ASSAY::IN-VIVO CHLORAMPHENICOL ACETYLTRANSFERASE (CAT) ASSAY
REPORTER GENE ASSAY::IN-VIVO GENE EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO GFP EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO LACZ EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO LUCIFERASE EXPRESSION ASSAY
REPORTER GENE ASSAY::RABBIT BETA-GLOBIN EXPRESSION ASSAY
REPORTER GENE ASSAY::SECRETED ALKALINE PHOSPHATASE (SEAP) ASSAY
REPORTER GENE ASSAY::SITE-SPECIFIC STABLE TRANSFECTION GFP ASSAY BY CRE-LOX RECOMBINATION
REPORTER GENE ASSAY::STABLE TRANSFECTION CAT ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION DSRED ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION LACZ ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION LUCIFERASE ASSAY
REPORTER GENE ASSAY::STABLY INCORPORATED GFP TRANSGENE ASSAY
REPORTER GENE ASSAY::TARGETED IN-VIVO EXPRESSION ASSAY BY IN UTERO ELECTROPORATION
REPORTER GENE ASSAY::TARGETED IN-VIVO GENE EXPRESSION ASSAY BY NON-VIRAL INJECTION
REPORTER GENE ASSAY::TARGETED IN-VIVO GFP EXPRESSION ASSAY BY VIRAL INJECTION
REPORTER GENE ASSAY::TARGETED IN-VIVO LACZ EXPRESSION ASSAY BY VIRAL INJECTION
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION GFP ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION HUMAN GROWTH HORMONE ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION LACZ ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION LUCIFERASE ASSAY
REPORTER GENE ASSAY::UNKNOWN
REPORTER GENE ASSAY::VIRAL INFECTION LUCIFERASE ASSAY
RNA EXPRESSION ASSAY::IN-VITRO TRANSCRIPTION ASSAY WITH DETECTION BY PRIMER EXTENSION
RNA EXPRESSION ASSAY::NORTHERN BLOT
RNA EXPRESSION ASSAY::PRIMER EXTENSION ANALYSIS WITH POLY(A)+ RNA
RNA EXPRESSION ASSAY::REAL TIME PCR
RNA EXPRESSION ASSAY::REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION (RT-PCR)
RNA EXPRESSION ASSAY::RNASE PROTECTION ASSAY (RPA)
RNA EXPRESSION ASSAY::WHOLE-MOUNT IN SITU HYBRIDIZATION
RNA STABILITY ASSAY::RNA SYNTHESIS BLOCKING
SELEX
SEQUENCE CONSERVATION::CO-EXPRESSED GENE CONSERVATION
SEQUENCE CONSERVATION::CONSERVATION FOUND BY ALIGNMENT
SEQUENCE CONSERVATION::ORTHOLOGOUS GENE CONSERVATION
SITE-DIRECTED MUTAGENESIS
UNKNOWN::CHROMATIN IMMUNOPRECIPITATION (CHIP)
UNKNOWN::UNKNOWN
YEAST ONE-HYBRID
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