The EPAS1_schodel project in PAZAR Help

Description

Schödel J, Oikonomopoulos S, Ragoussis J, Pugh CW et al. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq. Blood 2011 Jun 9;117(23):e207-17. Using chromatin immunoprecipitation linked to high throughput sequencing, we identify HIF-binding sites across the genome, independently of gene architecture

Statistics

Regulated genes (or markers): 281
Regulatory sequences (genomic): 301
Regulatory sequences (artificial): 0
Transcription factors: 1
Transcription factor profiles: 0
Annotated publications: 1

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Homo sapiens
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5S ribosomal RNA ENSG00000252653
5S ribosomal RNA ENSG00000201610
5S ribosomal RNA ENSG00000212505
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 ENSG00000170525
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 ENSG00000114268
actin-like 7B ENSG00000148156
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 ENSG00000136044
ADP-ribosylation factor 1 pseudogene 3 ENSG00000253885
AHNAK nucleoprotein ENSG00000124942
alcohol dehydrogenase 5 , chi polypeptide, pseudogene 2 ENSG00000232676
aldehyde oxidase 2 pseudogene ENSG00000243478
aldo-keto reductase family 1, member E2 ENSG00000165568
aldolase A, fructose-bisphosphate ENSG00000149925
ankyrin repeat domain 37 ENSG00000186352
archaelysin family metallopeptidase 1 ENSG00000174945
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 ENSG00000072818
argininosuccinate synthetase 1 pseudogene 7 ENSG00000236893
aryl hydrocarbon receptor interacting protein-like 1 ENSG00000129221
AT hook, DNA binding motif, containing 1 ENSG00000126705
ATPase, class II, type 9A ENSG00000054793
Bardet-Biedl syndrome 9 ENSG00000122507
basic helix-loop-helix family, member e40 ENSG00000134107
BCL2/adenovirus E1B 19kDa interacting protein 3-like ENSG00000104765
breast carcinoma amplified sequence 3 ENSG00000141376
BTB and CNC homology 1, basic leucine zipper transcription factor 1 ENSG00000156273
butyrobetaine 1 ENSG00000129151
C1D nuclear receptor corepressor ENSG00000197223
carbonic anhydrase IV ENSG00000167434
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 ENSG00000164442
chaperonin containing TCP1, subunit 4 pseudogene 1 ENSG00000242703
chaperonin containing TCP1, subunit 7 pseudogene 2 ENSG00000249958
chemokine receptor 7 ENSG00000144476
chromodomain helicase DNA binding protein 1-like ENSG00000131778
chromodomain helicase DNA binding protein 6 ENSG00000124177
chromodomain protein, Y-like 2 ENSG00000166446
chromosome 1 open reading frame 116 ENSG00000182795
chromosome 11 open reading frame 49 ENSG00000149179
chromosome 14 open reading frame 43 ENSG00000156030
chromosome 17 open reading frame 64 ENSG00000141371
chromosome 3 open reading frame 14 ENSG00000114405
chromosome 3 open reading frame 21 ENSG00000173950
chromosome 3 open reading frame 32 ENSG00000125046
chromosome 4 open reading frame 3 ENSG00000164096
chromosome 6 open reading frame 105 ENSG00000111863
chromosome 6 open reading frame 208 ENSG00000231690
chromosome 6 open reading frame 70 ENSG00000130023
chromosome 7 open reading frame 10 ENSG00000175600
chromosome 7 open reading frame 68 ENSG00000135245
coiled-coil domain containing 58 ENSG00000160124
core-binding factor, runt domain, alpha subunit 2; translocated to, 3 ENSG00000129993
cut-like homeobox 1 ENSG00000160967
CXXC finger protein 5 ENSG00000171604
CYP1B1 antisense RNA 1 ENSG00000232973
cysteine-serine-rich nuclear protein 1 ENSG00000144655
cytochrome P450, family 27, subfamily C, polypeptide 1 ENSG00000186684
DEAH box polypeptide 32 ENSG00000089876
death-associated protein kinase 2 ENSG00000035664
deleted in azoospermia-like ENSG00000092345
dermatopontin ENSG00000143196
desmoplakin ENSG00000096696
dishevelled associated activator of morphogenesis 1 ENSG00000100592
disrupted in renal carcinoma 3 ENSG00000231672
DNA-damage-inducible transcript 4 ENSG00000168209
DNA-damage-inducible transcript 4-like ENSG00000145358
DnaJ homolog, subfamily B, member 6 ENSG00000105993
DnaJ homolog, subfamily C, member 24 ENSG00000170946
Down syndrome cell adhesion molecule ENSG00000171587
dynamin 2 ENSG00000079805
dynein, axonemal, heavy chain 2 ENSG00000183914
dynein, light chain, LC8-type 1 ENSG00000088986
dynein, light chain, roadblock-type 1 ENSG00000125971
dystonin ENSG00000151914
E74-like factor 3 ENSG00000163435
early B-cell factor 1 ENSG00000164330
egl nine homolog 3 ENSG00000129521
EH-domain containing 2 ENSG00000024422
Enah/Vasp-like ENSG00000196405
endothelin converting enzyme 1 ENSG00000117298
enolase 1, ENSG00000074800
epidermal growth factor receptor ENSG00000146648
epithelial splicing regulatory protein 2 ENSG00000103067
ERO1-like ENSG00000197930
Ewing tumor-associated antigen 1 ENSG00000143971
F-box and WD repeat domain containing 7 ENSG00000109670
F-box protein 16 ENSG00000214050
F-box protein 21 ENSG00000135108
family with sequence similarity 129, member B ENSG00000136830
family with sequence similarity 13, member A ENSG00000138640
family with sequence similarity 162, member A ENSG00000114023
family with sequence similarity 174, member B ENSG00000185442
family with sequence similarity 65, member C ENSG00000042062
fatty acid binding protein 5 ENSG00000164687
FBJ murine osteosarcoma viral oncogene homolog ENSG00000170345
fem-1 homolog c ENSG00000145780
ferritin, heavy polypeptide 1 pseudogene 20 ENSG00000226564
forkhead box A1 ENSG00000129514
forkhead box L1 ENSG00000176678
fucosyltransferase 11 ENSG00000196968
FYVE, RhoGEF and PH domain containing 5 ENSG00000154783
G protein-coupled receptor 37 like 1 ENSG00000170075
G protein-coupled receptor 98 ENSG00000164199
G protein-coupled receptor, family C, group 5, member A ENSG00000013588
glucan , branching enzyme 1 ENSG00000114480
glucose-6-phosphate isomerase ENSG00000105220
glucose-fructose oxidoreductase domain containing 2 ENSG00000141098
glyceraldehyde-3-phosphate dehydrogenase ENSG00000111640
grainyhead-like 2 ENSG00000083307
gremlin 2 ENSG00000180875
growth regulation by estrogen in breast cancer 1 ENSG00000196208
GTF2I repeat domain containing 2B ENSG00000174428
guanine nucleotide binding protein , gamma 7 ENSG00000176533
HCLS1 binding protein 3 ENSG00000118960
heat shock transcription factor 4 ENSG00000102878
heparan sulfate 6-O-sulfotransferase 3 ENSG00000185352
high mobility group box 1 pseudogene 38 ENSG00000243877
histone cluster 1, H4h ENSG00000158406
hypoxia inducible factor 1, alpha subunit ENSG00000100644
ilvB -like ENSG00000105135
inhibin, beta A ENSG00000122641
insulin-like growth factor 2 mRNA binding protein 3 ENSG00000136231
integrin, alpha 5 ENSG00000161638
integrin, beta 5 ENSG00000082781
interferon regulatory factor 2 binding protein 2 ENSG00000168264
interleukin 6 receptor ENSG00000160712
iroquois homeobox 1 ENSG00000170549
kelch domain containing 4 ENSG00000104731
keratin 19 ENSG00000171345
keratin 7 ENSG00000135480
keratin 80 ENSG00000167767
KIAA0182 ENSG00000131149
KIAA0195 ENSG00000177728
KIAA0355 ENSG00000166398
Kruppel-like factor 10 ENSG00000155090
lactate dehydrogenase A ENSG00000134333
leprecan-like 1 ENSG00000090530
leucine, glutamate and lysine rich 1 ENSG00000178110
low density lipoprotein receptor-related protein 1 ENSG00000123384
lysine -specific demethylase 6B ENSG00000132510
lysyl oxidase-like 2 ENSG00000134013
mab-21-like 3 ENSG00000173212
MAM domain containing glycosylphosphatidylinositol anchor 2 ENSG00000139915
membrane-associated ring finger 10 ENSG00000173838
methyltransferase like 11A ENSG00000148335
microRNA 24-2 ENSG00000209707
microRNA 30d ENSG00000199153
microRNA 365-1 ENSG00000199130
microRNA 656 ENSG00000207959
MIR210 host gene ENSG00000247095
MT-RNR2-like 1 ENSG00000256618
MTND6 pseudogene 7 ENSG00000224695
mucin 5AC, oligomeric mucus/gel-forming ENSG00000215182
myeloid/lymphoid or mixed-lineage leukemia 5 ENSG00000005483
myocyte enhancer factor 2A ENSG00000068305
myxovirus ENSG00000183486
N-myc downstream regulated 1 ENSG00000104419
NECAP endocytosis associated 1 ENSG00000089818
NEDD4 binding protein 3 ENSG00000145911
non-protein coding RNA 160 ENSG00000230978
nuclear apoptosis inducing factor 1 ENSG00000171169
nuclear paraspeckle assembly transcript 1 ENSG00000245532
nuclear receptor corepressor 2 ENSG00000196498
nuclear receptor subfamily 5, group A, member 2 ENSG00000116833
nucleolar protein 12 ENSG00000100101
nucleolar protein 3 ENSG00000140939
nucleoporin 210kDa ENSG00000132182
olfactomedin-like 3 ENSG00000116774
PDZ and LIM domain 2 ENSG00000120913
peptidylprolyl isomerase A pseudogene 3 ENSG00000235044
peroxidasin homolog ENSG00000130508
peroxiredoxin 2 ENSG00000167815
peroxisome proliferator-activated receptor gamma ENSG00000132170
phosphofructokinase, platelet ENSG00000067057
phospholipase A2, group XV ENSG00000103066
phospholipase B1 ENSG00000163803
phosphoprotein associated with glycosphingolipid microdomains 1 ENSG00000076641
plakophilin 2 ENSG00000057294
platelet-derived growth factor beta polypeptide ENSG00000100311
pleckstrin homology-like domain, family A, member 1 ENSG00000139289
POC1 centriolar protein homolog B ENSG00000139323
podocalyxin-like ENSG00000128567
polymerase , delta 2, regulatory subunit 50kDa pseudogene 1 ENSG00000213730
potassium channel tetramerisation domain containing 11 ENSG00000213859
potassium large conductance calcium-activated channel, subfamily M, alpha member 1 ENSG00000156113
potassium voltage-gated channel, shaker-related subfamily, member 5 ENSG00000130037
prickle homolog 2 ENSG00000163637
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 ENSG00000152952
proliferation-associated 2G4 pseudogene 4 ENSG00000230457
prolyl 4-hydroxylase, alpha polypeptide I ENSG00000122884
protein phosphatase 1, regulatory subunit 3C ENSG00000119938
protein phosphatase, Mg2+/Mn2+ dependent, 1D ENSG00000170836
protein tyrosine phosphatase, receptor type, N polypeptide 2 ENSG00000155093
purinergic receptor P2Y, G-protein coupled, 2 ENSG00000175591
Pvt1 oncogene ENSG00000249859
pyridoxamine 5'-phosphate oxidase ENSG00000108439
pyruvate dehydrogenase kinase, isozyme 1 ENSG00000152256
pyruvate kinase, muscle ENSG00000067225
quaking homolog, KH domain RNA binding ENSG00000112531
quiescin Q6 sulfhydryl oxidase 1 ENSG00000116260
RAD23 homolog B ENSG00000119318
RAD51 homolog C ENSG00000108384
RAD51-like 1 ENSG00000182185
radial spoke head 9 homolog ENSG00000172426
Ral GEF with PH domain and SH3 binding motif 2 ENSG00000116191
RAP2B, member of RAS oncogene family ENSG00000181467
Ras association domain family member 3 ENSG00000153179
regulating synaptic membrane exocytosis 4 ENSG00000101098
Rho GTPase activating protein 26 ENSG00000145819
ring finger protein 19A ENSG00000034677
ring finger protein, transmembrane 1 ENSG00000189050
RNA, U2 small nuclear 3, pseudogene ENSG00000222076
RNA, U7 small nuclear 76 pseudogene ENSG00000239004
RNA, U7 small nuclear 85 pseudogene ENSG00000238884
round spermatid basic protein 1 ENSG00000081019
S100 calcium binding protein A4 ENSG00000196154
scavenger receptor class B, member 1 ENSG00000073060
SEC14-like 2 ENSG00000100003
sema domain, immunoglobulin domain 4B ENSG00000185033
sema domain, immunoglobulin domain 4F ENSG00000135622
sema domain, seven thrombospondin repeats 5B ENSG00000082684
SERTA domain containing 1 ENSG00000197019
SH3 and multiple ankyrin repeat domains 2 ENSG00000162105
SH3 domain containing ring finger 3 ENSG00000172985
small nuclear RNA activating complex, polypeptide 1, 43kDa ENSG00000023608
Small nucleolar RNA U3 ENSG00000252299
solute carrier family 28 , member 1 ENSG00000156222
solute carrier family 38, member 2 ENSG00000134294
solute carrier family 44, member 3 ENSG00000143036
solute carrier family 45, member 3 ENSG00000158715
solute carrier family 6 , member 6 ENSG00000131389
solute carrier family 7 , member 5 ENSG00000103257
solute carrier family 9 , member 9 ENSG00000181804
spleen tyrosine kinase ENSG00000165025
Src homology 2 domain containing adaptor protein B ENSG00000107338
SRY -box 9 ENSG00000125398
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 ENSG00000008513
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 ENSG00000148488
stanniocalcin 2 ENSG00000113739
stearoyl-CoA desaturase ENSG00000099194
sulfatase modifying factor 1 ENSG00000144455
SWAP switching B-cell complex 70kDa subunit ENSG00000133789
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 ENSG00000153147
testis expressed 14 ENSG00000121101
thrombospondin, type I, domain containing 7B ENSG00000144229
thyroglobulin ENSG00000042832
transducin-like enhancer of split 1 ENSG00000196781
transducin-like enhancer of split 4 ENSG00000106829
transferrin pseudogene 1 ENSG00000242337
transferrin receptor ENSG00000072274
transforming growth factor, beta-induced, 68kDa ENSG00000120708
translocation associated membrane protein 2 ENSG00000065308
transmembrane protease, serine 3 ENSG00000160183
transmembrane protein 189 ENSG00000240849
transmembrane protein 44 ENSG00000145014
tripartite motif containing 33 ENSG00000197323
tripartite motif containing 37 ENSG00000108395
TSC22 domain family, member 2 ENSG00000196428
tsukushi small leucine rich proteoglycan homolog ENSG00000182704
tumor protein p63 regulated 1 ENSG00000188001
two pore segment channel 2 ENSG00000162341
U1 spliceosomal RNA ENSG00000200975
U4 spliceosomal RNA ENSG00000201379
U4 spliceosomal RNA ENSG00000199643
U6 spliceosomal RNA ENSG00000202341
U6 spliceosomal RNA ENSG00000201104
U6 spliceosomal RNA ENSG00000223047
ubiquitin C ENSG00000150991
ubiquitin specific peptidase 32 ENSG00000170832
ubiquitin-conjugating enzyme E2D 2 ENSG00000131508
ubiquitin-conjugating enzyme E2E 1 ENSG00000170142
UBX domain protein 10 ENSG00000162543
v-crk sarcoma virus CT10 oncogene homolog -like ENSG00000099942
v-maf musculoaponeurotic fibrosarcoma oncogene homolog ENSG00000178573
vacuole membrane protein 1 ENSG00000062716
WD repeat and SOCS box containing 1 ENSG00000109046
WNT1 inducible signaling pathway protein 1 ENSG00000104415
zinc finger protein 292 ENSG00000188994
zinc finger protein 572 ENSG00000180938
zinc finger, SWIM-type containing 4 ENSG00000132003
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EPAS1_HUMAN ENST00000460015
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15688014
COMPILED
COMPUTATIONAL PREDICTION
DNASE I FOOTPRINTING
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::DIRECT GEL SHIFT
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::DIRECT GEL SHIFT WITH WESTERN BLOT DETECTION
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::GEL SHIFT COMPETITION
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::SUPERSHIFT
ELECTROPHORETIC MOBILITY SHIFT ASSAY (EMSA)::UNKNOWN
EMSA
EXPERT CURATED::LITERATURE DERIVED
GENE CO-EXPRESSION::CO-EXPRESSED GENES DETERMINED THROUGH REPORTER GENE EXPERIMENTS
IN-VIVO HUMAN CD4 ASSAY
MUTAGENESIS::EXONUCLEASE DIGESTION
MUTAGENESIS::EXONUCLEASE III DIGESTION
MUTAGENESIS::OLIGONUCLEOTIDE SYNTHESIS
MUTAGENESIS::PCR
MUTAGENESIS::RESTRICTION ENDONUCLEASE DIGESTION
MUTAGENESIS::SITE-DIRECTED
MUTAGENESIS::UNKNOWN
N/A
NA
PROTEIN BINDING ASSAY :: CHROMATIN IMMUNOPRECIPITATION WITH TAG SEQUENCING (CHIP-TS)
PROTEIN BINDING ASSAY::CHROMATIN IMMUNOPRECIPITATION (CHIP)
PROTEIN BINDING ASSAY::CHROMATIN IMMUNOPRECIPITATION WITH TAG SEQUENCING (CHIP-TS)
PROTEIN BINDING ASSAY::DNA-PROTEIN PRECIPITATION ASSAY
PROTEIN BINDING ASSAY::DNA-PROTEIN PRECIPITATION ASSAY WITH ELISA DETECTION
PROTEIN BINDING ASSAY::DNASE FOOTPRINTING ASSAY
PROTEIN BINDING ASSAY::DNASE FOOTPRINTING COMPETITION ASSAY
PROTEIN BINDING ASSAY::IN-VIVO FOOTPRINTING ASSAY
PROTEIN BINDING ASSAY::METHYLATION INTERFERENCE
PROTEIN BINDING ASSAY::METHYLATION INTERFERENCE ASSAY
PROTEIN BINDING ASSAY::UNKNOWN
PROTEIN BINDING ASSAY::WESTERN BLOT ASSAY
PROTEIN BINDING ASSAY::YEAST 1-HYBRID ASSAY
PROTEIN EXPRESSION ASSAY::ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA)
PROTEIN EXPRESSION ASSAY::INDIRECT IMMUNOFLUORESCENCE
PROTEIN EXPRESSION ASSAY::LUCIFERASE EXPRESSION ASSAY
PROTEIN EXPRESSION ASSAY::WESTERN BLOT ASSAY
REPORTER GENE ASSAY
REPORTER GENE ASSAY:: TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY
REPORTER GENE ASSAY:: TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY WITH ELISA DETECTION
REPORTER GENE ASSAY::BETA-GLOBIN EXPRESSION ASSAY
REPORTER GENE ASSAY::CHLORAMPHENICOL ACETYLTRANSFERASE (CAT) ASSAY
REPORTER GENE ASSAY::DUAL LUCIFERASE REPORTER GENE ASSAY
REPORTER GENE ASSAY::IN-VITRO VIRUS REPLICATION ASSAY
REPORTER GENE ASSAY::IN-VIVO CHLORAMPHENICOL ACETYLTRANSFERASE (CAT) ASSAY
REPORTER GENE ASSAY::IN-VIVO GENE EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO GFP EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO LACZ EXPRESSION ASSAY
REPORTER GENE ASSAY::IN-VIVO LUCIFERASE EXPRESSION ASSAY
REPORTER GENE ASSAY::RABBIT BETA-GLOBIN EXPRESSION ASSAY
REPORTER GENE ASSAY::SECRETED ALKALINE PHOSPHATASE (SEAP) ASSAY
REPORTER GENE ASSAY::SITE-SPECIFIC STABLE TRANSFECTION GFP ASSAY BY CRE-LOX RECOMBINATION
REPORTER GENE ASSAY::STABLE TRANSFECTION CAT ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION DSRED ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION LACZ ASSAY
REPORTER GENE ASSAY::STABLE TRANSFECTION LUCIFERASE ASSAY
REPORTER GENE ASSAY::STABLY INCORPORATED GFP TRANSGENE ASSAY
REPORTER GENE ASSAY::TARGETED IN-VIVO EXPRESSION ASSAY BY IN UTERO ELECTROPORATION
REPORTER GENE ASSAY::TARGETED IN-VIVO GENE EXPRESSION ASSAY BY NON-VIRAL INJECTION
REPORTER GENE ASSAY::TARGETED IN-VIVO GFP EXPRESSION ASSAY BY VIRAL INJECTION
REPORTER GENE ASSAY::TARGETED IN-VIVO LACZ EXPRESSION ASSAY BY VIRAL INJECTION
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION GENE EXPRESSION ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION GFP ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION HUMAN GROWTH HORMONE ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION LACZ ASSAY
REPORTER GENE ASSAY::TRANSIENT TRANSFECTION LUCIFERASE ASSAY
REPORTER GENE ASSAY::UNKNOWN
REPORTER GENE ASSAY::VIRAL INFECTION LUCIFERASE ASSAY
RNA EXPRESSION ASSAY::IN-VITRO TRANSCRIPTION ASSAY WITH DETECTION BY PRIMER EXTENSION
RNA EXPRESSION ASSAY::NORTHERN BLOT
RNA EXPRESSION ASSAY::PRIMER EXTENSION ANALYSIS WITH POLY(A)+ RNA
RNA EXPRESSION ASSAY::REAL TIME PCR
RNA EXPRESSION ASSAY::REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION (RT-PCR)
RNA EXPRESSION ASSAY::RNASE PROTECTION ASSAY (RPA)
RNA EXPRESSION ASSAY::WHOLE-MOUNT IN SITU HYBRIDIZATION
RNA STABILITY ASSAY::RNA SYNTHESIS BLOCKING
SELEX
SEQUENCE CONSERVATION::CO-EXPRESSED GENE CONSERVATION
SEQUENCE CONSERVATION::CONSERVATION FOUND BY ALIGNMENT
SEQUENCE CONSERVATION::ORTHOLOGOUS GENE CONSERVATION
SITE-DIRECTED MUTAGENESIS
UNKNOWN::CHROMATIN IMMUNOPRECIPITATION (CHIP)
UNKNOWN::UNKNOWN
YEAST ONE-HYBRID
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